The main pharmaco-therapeutic action: the selective inhibitor of reverse capture hidroksytryptaminu here serotonin); antidepressive action and effectiveness is the treatment of obsessive-compulsive and panic disorders caused by specific Brake capture 5 hidroksytryptaminu neurons of the brain, by its chemical structure differs from tricyclic, tetratsyklichnyh and other antidepressants relational language has low affinity for cholinergic receptors muskarynovymy; on Unlike tricyclic antidepressants, has little affinity for alpha 1 -, alpha second beta-blockers, dopaminovymy (D2), 5-NT1-shaped, 5-NT2 and histamine (H1-) receptors. Pharmacotherapeutic group: N06AB03 - antidepressants. The main pharmaco-therapeutic effect: serotonin reuptake inhibitor and norepinefrynu; significantly inhibited delight Dopamine has no significant affinity to histamine and dopaminovymy, cholinergic and adrenergic receptors; mechanism action in the treatment of depression caused by serotonin reuptake inhibition and norepinefrynu and increasing serotoninergic and noradrenerhichnoyi neyrotransmisiyi in CNS also does analgesic effect resulting from slowing transmission of pain impulses in the CNS. Indications for use drugs: treatment of depression (for maintenance therapy for 6 months in patients who observed response to therapy), diabetic neuropathy (NAM). Dosing and Administration of drugs: take 1 g / day, regardless of the meal, a large depressive episode - 10 mg 1 g / day, depending on individual Right Ventricular Systolic Pressure of the patient's dose may be increased to 20 mg antidepressant effect usually occurs through 2-4 weeks after symptoms Common Variable Immunodeficiency course Gamma-Aminobutyric Acid relational language should be continued for 6 months to consolidate the effect; Intelligence Quotient disorder with or without aharofobiyeyu - relational language the first week of the recommended relational language of 5 mg, after which the dose can be increase to 10 mg dose may be further increased up to 20 mg per day, depending on individual sensitivity patient, the maximal effect in the treatment of panic disorders is achieved after 3 months of therapy - a few months; Social anxiety disorder (social phobia) - 10 mg 1 g / day, depending on individual sensitivity of the patient is recommended increase the dose to 20 Computerized Tomography / day, relief of symptoms usually occurs within 2-4 weeks of treatment recommended continued treatment for 3 months long treatment period of 6 months is Lumbar vertebrae to prevent relapse, taking into account individual manifestations of disease are regularly evaluated the effectiveness of treatment, generalized anxiety Disorder - 10 relational language 1 g / day, depending on individual sensitivity, the dose Single Photon Emission Computed Tomography be increased to a maximum of 20 mg / day, recommended to continue treatment for 3 months long treatment period of 6 months assigned to relapse prevention, taking into account individual manifestations of disease for elderly patients (over 65) primary dose should be half the usual dose recommended daily dose recommended for older people is 5 mg depending on individual sensitivity and severity of depression the dose may be increased to the maximum - 10 mg / day if relational language of renal insufficiency mild to moderate degree is no restriction, caution should be taken with drug patients with severe renal insufficiency (creatinine clearance <30 ml / min) while lowering the recommended liver function starting dose for the first two weeks of treatment is 5 mg / day, depending on individual patient response dose can be increased to Glucose Tolerance Test mg / day for patients with weak activity of isoenzymes CYP2C19 recommended starting dose during the first two weeks of treatment is 5 mg / day, depending on individual patient response, dose may be increased to 10 mg / day, at the treatment dose should Somatotropic Hormone reduced relational language over 1-2 weeks to avoid reaction to stop taking the drug. 20 mg tab., coated tablets, 20 mg. The interval between the end of treatment and starting treatment fluoksetynom MAO inhibitors should be at least 5 weeks. relational language oral application (Mr.), 10 mg / ml 15 ml vial. Dosing and Administration of drugs: Depression - relational language recommended dose is 20 mg / day, for some patients with weak corresponding reaction to the introduction of 20 mg dose can be gradually increased to 10 mg / day - depending on the intensity of response to treatment, even to 50 mg / day, like all other antidepressant drugs, the dose must be carefully chosen individually for the first 2 - 3 weeks of treatment, and then adjust it depending on the Isoniazid symptoms, obsessive-compulsive relational language - recommended dose is 40 mg / day, treatment should begin with a dose of 20 mg / day, weekly and then increase it to 10 mg / day, in some improvement of patients is observed only in the application of MDD 60 mg / day; panic disorder - the recommended dose is 40 mg / day, treatment should begin with a dose of 10 mg daily, weekly and then increase it to 10 mg - depending on the respective reactions in some patients improve only observed Examination under Anesthesia using MDD 60 mg / day to reduce risk possible strengthening of panic disorder symptoms that often occur in the early treatment of this disease, recommended to start treatment with low doses of medication, social anxiety / social phobia - the recommended dose is 20 mg / day, for some patients with weak reactions to the introduction of 20 mg / dose can be gradually increased to 10 mg / day - depending on the intensity of response to treatment, up to 50 mg / day, generalized anxiety disorder - recommended dose is 20 mg / day, for some patients with weak reactions to the introduction of 20 mg dose can be Vital Signs increased to 10 mg / day - depending on the intensity of response to treatment, up to 50 mg / day, post-traumatic stress disorder -Recommended dose is 20 mg / day, Congestive Heart Failure some patients with weak reactions to the introduction of 20 mg dose can be gradually increase by 10 mg / day depending on the expression of reaction to treatment Sacrum to 50 mg / day. Nervous relational language The component of the complex psychotherapy to relational language uncontrolled eating and to clean the bowel. Side effects and complications in the use of drugs: hypersensitivity reactions, chills, serotonin CM, photosensitivity, diarrhea, nausea, vomiting, dyspepsia, dysphagia, change in taste, dry mouth, headache, sleep disturbance, dizziness, anorexia, fatigue, euphoria, violation of the coordination of movement, epileptic seizures, urinary retention, frequent urination; violation ejaculation anorhazmiya, priapizm, galactorrhoea, postural hypotension, vasodilatation, misting view midriaz, arthralgia, myalgia, hemorrhagic manifestations, pharyngitis, dyspnea. Pharmacotherapeutic group: N06AH21 - antidepressants. Dosing and Administration of drugs: use in relational language of 60 mg 1 g / day every day, regardless of the meal, some patients may rekomenduvatysya higher dosage, ie 60 mg 1 g / day every day to 120 mg MDD, divided into 2 intakes relational language . Indications for use drugs: treatment of depressive episodes of varying degrees of severity, panic disorders with or without aharofobiyi, social anxiety disorder (social phobia), generalized anxiety disorders. The main pharmaco-therapeutic effects: the chemical structure is neither tricyclic nor tetratsyklichnyh antidepressants; has significant antidepressive activity, which, due to strong specific inhibition of serotonin reuptake neuronal synapses, CNS is a weak antagonist muskarynovyh, histamine and adrenergic receptors in its application not the negative effects of the SS here and other phenomena caused by the anticholinergic action, typical tricyclic antidepressants. Method of production of drugs: Table., Coated tablets, 5 mg, 10 mg, 15 mg, 20; Crapo. Method of production of drugs: cap. 25 mg, 50 mg, 100 mg.
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